About Us  
Leadership
Events
Publications
Quality & Safety
News/Stories
For Media
Video
Careers
Volunteer
Locations - Maps
|  Directions  
|  Contact
MyChart
Quick Directory
Patient Support and Services
Your Child's Stay
Why Choose Children's
Visitor Information
eCards
Billing and Payment
Medical Records
Español
Patient Stories
Contact Us
Maps & Locations
Refer a Patient
Find a Doctor
Clinic Schedules
Education & Training
Clinical Trials & Research
Medical Staff
Calendar
Maps
Contact Directory
Our Impact
Research Centers & Services
Clinical & Translational Research
Principal Investigators
CHORI Leadership
Education Programs
Ways to Give
Volunteer
Donate Now
Foundation Events
UCSF Benioff Children's Foundation
Children's Hospital Oakland HomeDepartments & ServicesCenter for Applied Genomics (CAG)
Add This

Center for Applied Genomics (CAG)

The Center for Applied Genomics (CAG) is a genome center in the Research Institute at UCSF Benioff Children's Hospital Oakland. As a pediatric center devoted to research in biology and medicine, we are using functional genomic approaches to further the prevention and prediction of the evolution of disease and response to therapy. Our aim is to discover the genetic causes of prevalent childhood diseases and translate findings into medical innovations.

Find Us
Children's Hospital Oakland Research Institute
5700 Martin Luther King Jr Way
Oakland, CA 94609
Next Generation Sequencing Services

The Center for Applied Genomics focuses on the genetic and genomic research with an emphasis on next-generation sequencing (NGS). Work at the Center for Applied Genomics ranges from basic research to diagnostics, drug discovery and applications to public health.

Requests

We provide high-quality Next-Generation (Next-Gen) sequencing data, quickly, and at a reasonable cost. Send us an email us to request an information packet.

Index of Services 

Our facility offers state-of-the-art, Next-Gen services utilizing the 454 GS-FLX+ Titanium™, sequencing platform, which can be used in support of your research projects. We specialize in sequencing genes from pooled amplicons of immunogenetic complexes, including the human leukocyte antigen (HLA), and genes involved in cardiomyopathies. By utilizing amplicon-based Next-Gen technologies, we can provide fast and economical genomic research sequence support for immunogenomics, disease association, pharmacogenetics, population genetics and personalized medicine studies.

Our services include, but are not limited to:

  • HLA amplicon sequencing services - allelic typing to 6-8 digit resolution of class I and II genes (HLA-A, HLA-B, HLA-C, DRB1/3/4/5, DQB1, DQA1, DPB1, DPA1 in any combination of multiple or single genes)
  • KIR amplicon sequencing services – allelic typing of all KIR loci, including all exons and some upstream and intronic regions (available Spring 2013)
  • Genes involved in cardiomyopathies: NKX2-5, ISL1, MEF2C, GATA4, GATA5, GATA6, ZFPM2, FOXH1, FGF8, CRKL
  • Ultra-deep sequencing providing highly sensitive detection levels without any bias
  • Expertise Using Roche GS FLX+ for long reads
  • Custom amplicon sequencing services (call to discuss)
  • Quality data and reasonable rates and turnaround time

Our amplicon sequencing is based on ultra-deep sequencing of PCR products and can be used for analyzing genetic variations within a population. The long read lengths and data accuracy of Roche GS FLX+ makes the technology the gold standard for amplicon sequencing. As each molecule within a pool of amplicons can be sequenced individually, the technology has the power to detect rare variants with detection limits of at least 0.5 percent.

Additional Information

Our Certifications

  • Clinical Laboratory Improvement Amendment (CLIA)
  • College of American Pathologists (CAP)
  • State of CA Laboratory Field Services
  • American Society of Histocompatibility and Immunogenetics (ASHI)
  • American Board of Histocompatibility and Immunogenetics (ABHI)
  • America Board of Molecular Genetics (ABMG)

 

Related Departments / Services
Hemoglobinopathy Laboratory
HLA/Immunogenetics Laboratory
Pathology & Laboratory Medicine
Events
CPR Certification Class - Oakland
Monday, December 16, 2019
Pediatric Sports Medicine Conference: Managing Pain in Your Young Athletes After Injuries
Saturday, January 11, 2020
CPR Certification Class - Walnut Creek
Monday, January 13, 2020
CPR Certification Class - Oakland
Monday, February 10, 2020
CPR Certification Class - Walnut Creek
Monday, March 16, 2020
CPR Certification Class - Oakland
Monday, April 20, 2020
CPR Certification Class - Walnut Creek
Monday, May 18, 2020
CPR Certification Class - Oakland
Monday, June 15, 2020
CPR Certification Class - Walnut Creek
Monday, July 20, 2020
CPR Certification Class - Oakland
Monday, August 17, 2020
CPR Certification Class - Walnut Creek
Monday, September 21, 2020
CPR Certification Class - Oakland
Monday, October 19, 2020
CPR Certification Class - Walnut Creek
Monday, November 16, 2020
STAY CONNECTED:
DIRECTIONS
SECTIONS INFORMATION FOR
ABOUT US
I'D LIKE INFORMATION ON
ABOUT THIS SITE
Departments & Clinics
Physician Directory
Refer a Patient
Medical Education
Giving

Referring Physicians
Patients & Families
Visitors
Healthcare Professionals
Media
Job Seekers
Vendors
Donors
About Children's Hospital
About the UCSF Affiliation
Pricing Transparency
Notice of Privacy Practices
Careers
Contact Us
Volunteering
Finding a Doctor
Medical Education
eCards
Bill Pay
Events
Donations
Paginas en Espanol
Site Map
Disclaimer, Usage & Privacy

ASSOCIATED SITES
www.CHORI.org
Give.UCSFBenioffChildrens.org



© 2019 UCSF Benioff Children's Hospital Oakland
747 52nd Street, Oakland, CA 94609
510-428-3000
UCSF Benioff Children’s Hospitals rank among the nation’s top-tier pediatric medical centers, according to U.S. News & World Report
 

Loading... Loading...

Generalist Obstetrical Physician:

A residency-trained obstetrician and gynecologist, expert in diseases specific to women.