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Nahal Lalefar, MD
Pediatric Hematology-Oncology
Associate Hematologist Oncologist , Blood and Bone Marrow Transplant Program
Clinical Specialties: Hematopoietic cell transportation, Pediatric Oncology
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Department Location
Hematology Oncology
Walnut Creek Campus
2401 Shadelands Drive
Walnut Creek, CA 94598
Phone: (510) 428-3372
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Education & Training
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Medical School University of California, Davis, CA Residency UCSF-Fresno, Children’s Hospital of Central California, CA (Pediatrics) |
Board Certification Pediatrics Internship UCSF-Fresno, Children’s Hospital of Central California, CA Fellowship Children's Hospital & Research Center Oakland, CA (Pediatric Hematology Oncology) |
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Additional Information | Dr. Lalefar joined the clinical faculty in 2016 after completing her training with focused clinical and research work in transplantation. She continues her research on hematopoietic stem self-renewal utilizing Wnt with Robert Ryan, PhD at CHORI. Wnt is a protein that promotes maintenance of stem cells in a self-renewing state. She is expanding her research into translational studies that are synergistic with Dr. Ryan’s laboratory and Dr. Mark Walters’ stem cell program. Dr. Lalefar has developed nanodisks as a biomimetic delivery platform for stem cell expansion with the goal of promoting hematopoietic stem call self-renewal in the absence of differentiation. While early in her career, she has already received several honors and awards including a CIRM grant and recognition for her research and departmental leadership in addition to expert clinical care.
Selected Research and Publications:
- Lalefar N, Witkowski A, Simonsen J, Ryan R. A “Wnt-erized” morphogen transport vehicle induces hematopoietic stem and progenitor cell expansion. J Nanobiotechnology. 2016 Aug 23;14(1):66. PMID: 27553039 PMCID: PMC4995738
- Lalefar N, Walters M. Graft Failure after Hematopoietic Cell Transplantation for Hemoglobin Disorders: Successful Application of a Rescue Regimen. American Society of Hematology Annual Meeting online abstract. Blood: Volume 126, Issue 23. December 2015.
- Lalefar N, Hagar RW. A Comparison of Hematologic Parameters in Patients with Sickle Cell Disease Undergoing Red Cell Exchange Using Terumo BCT Spectra Optia and COBE Spectra Apheresis Systems. American Society of Hematology Annual Meeting online abstract. Blood: Volume 126, Issue 23. December 2015.
- Lalefar N, Raphael R. Thrombotic Disorders. Supportive Care in Pediatric Oncology. Eds. Feusner J, Hastings CH, Agrawal AK. Berlin: Springer 2015.
- Lalefar NR, Lubin, B. Sibling Donor Cord Blood Program: Children’s Hospital Research Center Oakland and Beyond. Stem Cell Banking, Stem Cell Biology and Regenerative Medicine. Ed. Dusko Ilic. Humana Press/Springer Science, New York, 2014.
- Lalefar NR, Ozeran JD. Iron overload in childhood cancer. Pediatric Blood & Cancer. 2012;58(7).
- Lalefar, N, Tablizo, M, Roberto L. Subpleural Cysts in Children with Down Syndrome (abstract). Journal of Investigative Medicine. Volume 58, Number 1. Pg 234-235. January 2010.
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