Treadwell, Marsha J., PhD

Marsha Treadwell


Mental Health & Child Development

Director, Northern California, Network of Care for Sickle Cell Disease

Co-Principal Investigator and Regional Director, Pacific Sickle Cell Regional Collaborative

Director, Hematology Behavioral Services

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Medical School

University of Washington, WA


(Post-doc Fellowship/Ped P)


University of Washington Medical Center, WA

Clinic Locations

My Work

About Me

Dr. Treadwell is the Co-Principal Investigator and Regional Director for the Pacific Sickle Cell Regional Collaborative (PSCRC), recently funded through HRSA’s Sickle Cell Disease Treatment Demonstration Program (SCDTDP). The PSCRC serves 10,000 children and adults with sickle cell disease (SCD) spanning eight western states and one U.S. territory. The PSCRC goals are: to increase the number of providers treating individuals with SCD; increase the number of providers prescribing disease modifying therapies, such as hydroxyurea; and increase the number of patients that are receiving regular care with providers knowledgeable about treating SCD. Dr. Treadwell directs all of the data management and shared measurement for the project, including the state leads’ efforts as they gather state level Medicaid data and clinical data for our minimum data set as well as overseeing patient/family education about hydroxyurea for the PSCRC and coordinating provider education in Northern California, in collaboration with the UCSF School of Medicine. Previously, she was Co-Principal Investigator and Project Director for the Northern California Network of Care for Sickle Cell Disease, also funded through the HRSA SCDTDP. That project aimed to improve the quality of care that individuals with SCD receive in the U.S. She worked with other SCDTDP grantees and the coordinating center to conduct quality improvement initiatives in relation to transition from pediatric to adult care, self-management support to improve adherence with medications and management of acute pain in emergency departments.

She has demonstrated expertise in community engagement with a range of stakeholders, as evidenced by direction of the HRSA grants and of a large field test - the Adult Sickle Cell Quality of Life Measurement (ASCQ-Me) information system that enrolled 561 adults with SCD from every region of the U.S. representing a diversity of urban, suburban, and rural populations as well as medical center and community-based settings. She participated in all phases of the ASCQ-Me formative research, including conceptualizing domains and conducting qualitative research (individual and focus group interviews) that informed item bank development with 122 patients with SCD and their providers. Dr. Treadwell is a Senior Scientist and co-Director of the Northern California Comprehensive Sickle Cell Center. She is internationally recognized for her work in research that links scientists, clinicians, and the sickle cell community. She has been PI or co-PI on several NIH grants. She originally received her K23 on psychobiological reactivity in sickle cell disease. She is the co-PI of the HRSA project Pacific Sickle Cell Regional Collaborative and the recently NIH-awarded SC-Links – Linking the Sickle Cell Community, Providers to improve sickle cell care. Dr. Treadwell has been a leader in the PHRESH and RuSH projects funded by the CDC. Dr. Treadwell has received NIH funding to develop sickle cell related quality of life instruments. Dr. Treadwell received NIH funding to understand attitudes and perspectives of genomic research and its implementation in Cameroon, Ghana, and Tanzania for sickle cell disease. As a leader in patient and community education, she has been funded by HRSA to develop methods to improve education concerning sickle cell trait for providers and the community. She received the Cooley’s Anemia award to address transition and self-management issues affecting the thalassemia community. In addition to her research activities, Dr. Treadwell directs behavioral science in the hematology division and the adolescent transition program.

Selected Research and Publications:

  1. Anie KA, Treadwell MJ, Grant AM, Dennis-Antwi JA, Asafo MK, Lamptey ME, Ojodu J, Yusuf C, Otaigbe A, Ohene-Frempong K. Community Engagement to Inform the Development of a Sickle Cell Counselor Training and Certification Program in Ghana. J Comm Genet, 2016 April 18.
  2. Treadwell MJ, Anie K, Grant A, Ofori-Acquah S, Ohene-Frempong K. Using Formative Research to Develop a Counselor Training Program for Newborn Screening in Ghana. J Genet Couns 2015; 24(2): 267-277.
  3. Treadwell MJ, Barreda F, Kaur K, Gildengorin G. Emotional distress, barriers to care and health related quality of life in sickle cell disease. J Clin Outcomes Manage 2015; Jan 22(1): 10 – 20.
  4. Wonkam A, Makani J, Ofori-Aquah S, Nnodu OE, Treadwell M, Royal C, Ohene-Frempong K; Members of the H3Africa Consortium. Sickle cell disease and H3Africa: enhancing genomic research on cardiovascular diseases in African patients. Cardiovasc J Afr. 2015 Mar-Apr;26(2 Suppl 1):S50-5.
  5. Treadwell M, Johnson S, Sisler I, Bitsko M, Gildengorin G, Medina R, Barreda F, Major K, Telfair J, Smith WR. Development of a sickle cell disease readiness for transition assessment. Int J Adolesc Med Health. 2015 Jul 30.
  6. Treadwell M, Johnson S, Sisler I, Bitsko M, Gildengorin G, Medina R, Barreda F, Major K, Telfair J, Smith WR. Self-efficacy and readiness for transition from pediatric to adult care in sickle cell disease. Int J Adolesc Med Health. 2015 Jul 30.
  7. Treadwell M, Hassell K, Levine R, Keller S. Adult Sickle Cell Quality of Life Measurement Information System (ASCQ-Me): Conceptual Model Based on Review of the Literature and Formative Research. Clin J Pain. 2014 Oct;30(10):902-14.
  8. Treadwell M, Bell M, Leibovich S, Barreda F, Marsh A, Gildengorin G, Morris C. Quality improvement initiative improves emergency department care for pediatric patients with sickle cell disease. J Clin Outcomes Manage. 2014 Feb;21(2):62-70.